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Intravenous administration of Reglan Injection diluted in a parenteral solution should be made slowly over a period of not less than 15 minutes.

Metoclopramide is contraindicated in patients with known sensitivity or intolerance to the drugMetoclopramide should not be used in epileptics or patients receiving other drugs which are likely to cause extrapyramidal reactionssince the frequency and severity of seizures or extrapyramidal reactions may be increased.

Experience with esophageal erosions and ulcerations is limitedbut healing has thus far been documented in one controlled trial using q.i.dtherapy at 15 mg/doseand this regimen should be used when lesions are presentso long as it is toleratedsee ADVERSE REACTIONSBecause of the poor correlation between symptoms and endoscopic appearance of the esophagustherapy directed at esophageal lesions is best guided by endoscopic evaluation.

If this medication has been used regularly for a long time or in high doseswithdrawal symptomssuch as dizzinessnervousnessheadachesmay occur if you suddenly stop using this medicationTo prevent withdrawal reactionsyour doctor may reduce your dose graduallyConsult your doctor or pharmacist for more detailsand report any withdrawal reactions right away.

Stop using Reglan and call your doctor at once if you have tremors or uncontrolled muscle movementsfeverstiff musclesconfusionsweatingfast or uneven heartbeatsrapid breathingdepressed moodthoughts of suicide or hurting yourselfhallucinationsanxietyagitationseizureor jaundiceyellowing of your skin or eyes

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