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Information about Zetia.
Zetia may be taken at the same time with fenofibrateor with a statin medication such as atorvastatinlovastatinsimvastatinpravastatinor fluvastatin.
Avoid eating foods that are high in fat or cholesterolZetia will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.
Ezetimibe has a mechanism of action that differs from those of other classes of cholesterol-reducing compoundsstatinsbile acid sequestrantsresinsfibric acid derivativesand plant stanolsThe molecular target of ezetimibe has been shown to be the sterol transporterNiemann-Pick C1-Like 1NPC1L1which is involved in the intestinal uptake of cholesterol and phytosterols.
EzetimibeZetiais a newly Food and Drug Administration(FDAapproved medication that selectively inhibits the intestinal absorption of cholesterol and related phytosterolsIt is approved for primary hypercholesterolemiaheterozygous familial and nonfamilial hypercholesterolemiaas monotherapy or in combination with 3-hydroxy-3-methylglutaryl coenzyme AHMG-CoAreductase inhibitorsstatinsIt is also indicated in combination with atorvastatin or simvastatin for homozygous familial hypercholesterolemia and as an adjunct to diet for homozygous sitosterolemia1
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