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Protease inhibitorsConcomitant use of protease inhibitors may increase the concentration of cytotoxic metabolitesUse of protease inhibitor-based regimens was found to be associated with a higher Incidence of infections and neutropenia in patients receiving cyclophosphamidedoxorubicinand etoposideCDEthan use of a Non-Nucleoside Reverse Transcriptase Inhibitor-based regimen.

If not used immediatelyfor microbiological integritycyclophosphamide solutions should be stored as described in Table 3:

Metabolism and Nutritionhyponatremiafluid retentionblood glucose increasedblood glucose decreased.

What are possible late side effects of treatment with cyclophosphamideWith the use of this drugthere is risk of developing side effects months or years after treatment has been completedIn rare instancesa secondary taladafil. malignancy may occur as a result of receiving this drugA secondary malignancy is a new and unrelated cancer that occurs in an individual as a result of previous treatment with radiation or chemotherapyPatients should ask their physician about the possibility of developing a secondary malignancy as a result of their treatment.

The following adverse reactions are discussed in more detail in other sections of the labeling.

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