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The metabolism of isoniazid may be increased in chronic alcoholics this may lead to reduced isoniazid effectiveness.

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You will need to avoid eating foods beverages that contain very high amounts of tyramine or histamine during your treatment with isoniazidThese foods and beverages include certain cheesesred wineand certain fishe.gtunaother tropical fishTalk to your doctor or dietitian about which foods you should avoid during your treatment or if you do not feel well after eating or drinking certain foods while taking isoniazid.

Isoniazid may interact with foods containing tyramine/histaminesuch as cheesered winecertain types of fishThis interaction may cause increased blood pressureflushing of the skinheadachedizzinessor fast/pounding heartbeatTell your doctor right away if any of these symptoms occurYour doctor may recommend that you follow a special diet while taking this medicationConsult your doctor for more details.

Keep all appointments with your doctor and the laboratoryYour doctor will order certain lab tests to check your response to isoniazid.

Serum concentrations of hepatic transaminases should be monitored whenever possible.

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