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Avoid other hepatotoxicdermatotoxicQT-prolonging drugsIncreased ocular toxicity with concomitant tamoxifenMay potentiate digoxincyclosporinemonitorMay need to reduce dose of concomitant insulin or antidiabetic drugsIncreased seizure risk with other antimalarialsegmefloquineIncreased toxicity with methotrexateMay affect antiepileptics.
It is important to take this medication exactly as prescribed by your doctorIf you miss a dosetake it as soon as possible and continue with your regular scheduleIf it is within 12 hours of your next doseskip the missed dose and continue with your regular dosing scheduleDo not take a double dose to make up for a missed oneIf you are not sure what to do after missing a dosecontact your doctor or pharmacist for advice.
Muscle weaknessCall your doctor if you notice any signs of unusual or unexpected muscular weakness.
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