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RespiratoryBronchitisbronchospasmbronchospasm aggravatedcoughdyspnealaryngitispneumonia.
Advise patients to be alert for the symptoms of congestive heart failure including shortness of breathunexplained weight gainor edema and to contact their healthcare provider if such symptoms occursee WARNINGS AND PRECAUTIONS
Severe skin reactionfeversore throatswelling in your face or tongueburning in your eyesskin pain followed by a red or purple skin rash that spreadsespecially in the face or upper bodyand causes blistering and peeling.
In patients who are known or suspected to be poor CYP2C9 metabolizersi.eCYP2C9*33based on genotype or previous history/experience with other CYP2C9 substratessuch as warfarinphenytoinadminister CELEBREX starting with half the lowest recommended doseAlternative management should be considered in JRA patients identified to be CYP2C9 poor metabolizerssee DOSAGE AND ADMINISTRATION and CLINICAL PHARMACOLOGY
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